The Latest from the AJRCCM & AJRCMB

AJRCCMDecember 1, 2011 AJRCCM

The December 1 American Journal of Respiratory and Critical Care Medicine features a Concise Clinical Review on the core cellular process of autophagy and its emerging links to pulmonary disease, as well as two pro/con editorials on research aimed at better understanding lung cancer. This issue of the journal also features original research on the impact of race on asthma treatment failures in the Asthma Clinical Research Network; intestinal injury and endotoxemia in children undergoing surgery for congenital heart disease; and the societal impact of single versus bilateral lung transplantation for COPD.

Researchers also present findings on screening and prevention of venous thromboembolism in critically ill patients, obstructive sleep apnea and systemic hypertension, and the cognitive defects induced by sleep fragmentation.

This issue’s “Images in Pulmonary, Critical Care, Sleep Medicine, and the Sciences” features images of idiopathic Cheyne-Stokes respiration in acute respiratory acidosis.

December 15, 2011 AJRCCM

The December 15 issue of the journal will include a concise clinical review on anthrax infection, as well as original research on telomere dysfunction and sustained inflammation in COPD; the high prevalence of multi-drug resistant non-fermenters in hospital-acquired pneumonia; altered microRNA processing in heritable pulmonary arterial hypertension; and the response of children with asthma to ambient particulate matter and tobacco smoke. Researchers also discuss the relationship between vitamin D, disease severity and airway remodeling in pediatric asthma; the evolution of dyspnea during exercise in COPD; gastroesophageal reflux therapy for idiopathic pulmonary fibrosis; and a trial of intrapleural adenoviral-mediated interferon-Beta2b gene transfer.

To read the issue in full, please visit http://ajrccm.atsjournals.org.

AJRCMBDecember 2011 AJRCMB

The December 2011 American Journal of Respiratory Cell and Molecular Biology features a pulmonary perspective on the usefulness of animal models of cigarette smoke-induced COPD, as well as a translational review article on pathways activated by Mycobacterium tuberculosis that target HIV-1 long terminal repeat.

Other original articles focus on the influenza virus’s inducement of IL-33 in murine lungs; Pneumocystis S-Adenosylmethionine transport; and the opposing effects of bone morphogenetic protein-2 and endothelin-1 on lung fibroblast chloride currents. Researchers also examine how connective tissue growth factor antibody therapy attenuates hyperoxia-induced lung injury in neonatal rats; up regulation of receptors for advanced glycation end-products by alveolar epithelium; and the molecular signature of a right heart failure program in chronic severe pulmonary hypertension.

To read the issue in full, visit http://ajrcmb.atsjournals.org.