AJRCMB HIGHLIGHTS Volume 62, Number 6, June 2020
TRANSLATIONAL REVIEW
Applications and Approaches for Three-Dimensional Precision-Cut Lung Slices: Disease Modeling and Drug Discovery
Hani N. Alsafadi, Franziska E. Uhl, Ricardo H. Pineda, Kolene E. Bailey, Mauricio Rojas, Darcy E. Wagner, and Melanie Königshoff
ARTICLES
Fibroblast Biology and Pulmonary Fibrosis
Active mTOR in Lung Epithelium Promotes Epithelial–Mesenchymal Transition and Enhances Lung Fibrosis
Minako Saito, Akihisa Mitani, Taro Ishimori, Naoya Miyashita, Hideaki Isago, Yu Mikami, Satoshi Noguchi, Megumi Tarui, and Takahide Nagase
Pulmonary Vascular Biology and Pulmonary Hypertension
Altered Lipid Domains Facilitate Enhanced Pulmonary Vasoconstriction after Chronic Hypoxia
Charles E. Norton, Laura Weise-Cross, Rosstin Ahmadian, Simin Yan, Nikki L. Jernigan, Michael L. Paffett, Jay S. Naik, Benjimen R. Walker, and Thomas C. Resta
Intermittent Hypoxia Augments Pulmonary Vasoconstrictor Reactivity through PKCβ/Mitochondrial Oxidant Signaling
Jessica B. Snow, Charles E. Norton, Michelle A. Sands, Laura Weise-Cross, Simin Yan, Lindsay M. Herbert, Joshua R. Sheak, Laura V. Gonzalez Bosc, Benjimen R. Walker, Nancy L. Kanagy, Nikki L. Jernigan, and Thomas C. Resta
Lung Innate and Adoptive Immunity/Pulmonary Infections
PD-1 Deficiency Promotes Macrophage Activation and T-helper cell type 1/T-helper cell type 17 Response in Pneumocystis Pneumonia
Chao Zhang, Heng-Mo Rong, Ting Li, Kan Zhai, and Zhao-Hui Tong
Orosomucoid-Like 3 Supports Rhinovirus Replication in Human Epithelial Cells
Yiping Liu, Yury A. Bochkov, Jens C. Eickhoff, Tianchen Hu, Nicholas A. Zumwalde, Jin Wen Tan,
Christopher Lopez, Paul S. Fichtinger, Thiruchelvi R. Reddy, Katherine A. Overmyer, Jennifer E. Gumperz, Joshua Coon, Sameer K. Mathur, James E. Gern, and Judith A. Smith
Lung Cancer/LAM
Adoptive T-Cell Transfer to Treat Lymphangioleiomyomatosis
Fei Han, Emilia R. Dellacecca, Levi W. Barse, Cormac Cosgrove, Steven W. Henning, Christian M. Ankney, Dinesh Jaishankar, Alexander Yemelyanov, Vera P. Krymskaya, Daniel F. Dilling, and I. Caroline Le Poole
AJRCMB HIGHLIGHTS Volume 63, Number 1, July 2020
TRANSLATIONAL REVIEW
Extracellular Vesicles: A New Frontier for Research in Acute Respiratory Distress Syndrome
Rahul Y. Mahida, Shotaro Matsumoto, and Michael A. Matthay
ARTICLES
Airway Inflammation and Asthma
Role of Isocitrate Dehydrogenase 2 on DNA Hydroxymethylation in Human Airway Smooth Muscle Cells
Bonnie H. Y. Yeung, Jessie Huang, Steven S. An, Julian Solway, Wayne Mitzner, and Wan-yee Tang
Antisense Oligonucleotides Targeting Jagged 1 Reduce House Dust Mite-induced Goblet Cell Metaplasia in the Adult Murine Lung
Michele Carrer, Jeff R. Crosby, Guizhen Sun, Chenguang Zhao, Sagar S. Damle, Steven G. Kuntz,
Brett P. Monia, Christopher E. Hart, and Tamar R. Grossman
Cysteinyl Leukotriene Synthesis via Phospholipase A2 Group IV Mediates Exercise-induced Bronchoconstriction and Airway Remodeling
Hiroshi Ueno, Toshiyuki Koya, Hiroyuki Takeuchi, Keisuke Tsukioka, Akira Saito, Yosuke Kimura, Masachika Hayashi, Satoshi Watanabe, Takashi Hasegawa, Masaaki Arakawa, and Toshiaki Kikuchi
Chronic Obstructive Pulmonary Disease
Serine Protease Imbalance in the Small Airways and Development of Centrilobular Emphysema in Chronic Obstructive Pulmonary Disease
Kiyoshi Uemasu, Naoya Tanabe, Kazuya Tanimura, Koichi Hasegawa, Tatsushi Mizutani, Yoko Hamakawa, Susumu Sato, Emiko Ogawa, Matthew J. Thomas, Machiko Ikegami, Shigeo Muro, Toyohiro Hirai, and Atsuyasu Sato
Acute Lung Injury
Maternal Vitamin D Deficiency Causes Sustained Impairment of Lung Structure and Function and Increases Susceptibility to Hyperoxia-induced Lung Injury in Infant Rats
Erica W. Mandell, Sharon Ryan , Gregory J. Seedorf, Tania Gonzalez, Bradford J. Smith, James C. Fleet, and Steven H. Abman
Pulmonary Vascular Biology and Pulmonary Hypertension
Basement Membrane Remodeling Controls Endothelial Function in Idiopathic Pulmonary Arterial Hypertension
Katharina Jandl, Leigh M. Marsh, Julia Hoffmann, Ayse Ceren Mutgan, Oliver Baum, Wilhelm Bloch,
Helene Thekkekara-Puthenparampil, Dagmar Kolb, Katharina Sinn, Walter Klepetko, Akos Heinemann, Andrea Olschewski, Horst Olschewski, and Grazyna Kwapiszewska
