Who's Who

HomeATS CommunityWho's Who ▶ Who's Who: Jaime L. Hook, MD
Who's Who: Jaime L. Hook, MD

  •  Your full title as you’d like it to appear.


Jaime Hook, MD, assistant professor in the Departments of Medicine and Microbiology


  • Three statements about you – two true, one false. (We tease each new Who’s Who with statements about each featured person – two of which are true, one of which is false, all to be revealed in the last answer.)

Jaime’s father was the fire chief of her hometown.

Jaime’s afraid of her own basement and refuses to go downstairs when it’s dark

Jaime was a ranked junior-golfer in Wisconsin.


  • Give us your ‘elevator pitch’ biography.


I grew up in Milwaukee and went to college and medical school at the University of Wisconsin in Madison.  I121015_hook-lab.jpg then moved to New York City where I completed my residency, fellowship, and postdoctoral research training at Columbia University Medical Center.  I had the good luck of carrying out my postdoctoral training in lung biology in Jahar Bhattacharya, MD’s lab.  After finishing that training, I moved to the Icahn School of Medicine at Mount Sinai in 2019 to start my independent research program.  I now have six fantastic people in my group, and our research focuses on mechanisms of lung alveolar damage and repair in response to inhaled influenza and staphylococci. I see patients as an attending physician on the inpatient pulmonary consult service.


  • What would you tell yourself as an Early Career Professional?


Read the book Deep Work, and then read it again.  The wonderful Patty Lee, MD gave this book to me a couple years ago, and it changed how I organize my day.  It really increased my productivity in a sustainable way.


  • If you weren’t in medicine, and were in a different industry altogether, what would you be?


Being a physician-scientist with my own lab is my dream job, so right now I’m just hoping to hang on to this for as long as I can.  But if I had to do something else, I’d work in government to try to improve the foster care and other public welfare systems.  As long as we’re dreaming, I’d love to get a chance to drive a Ferrari.  I know that’s not a job but it would be amazing.


  • What is your favorite way to spend a day off?


If that day off is on a weekend, then I like to spend it with my family – my husband, Adam, six-year-old son, Oliver, and one-year-old daughter, Anna.  We do pretty normal stuff like play sports, take walks, and visit grandparents.  If I have a day off on a weekday, then I like to make a pot of coffee and get lost in a good book – especially a biography.  My favorite is Robert Caro’s (unfinished!) series on Lyndon Johnson.


  • What areas of medicine are you most excited to see develop?


I’m excited to see the development of new, host-directed therapies for severe pneumonia that circumvent the problem of pathogen drug resistance.  The COVID-19 pandemic has boosted interest in this research, and it’s created a major opportunity for our community of clinical, basic, and translational investigators in lung disease to take a leading role in the development and testing of these new therapeutics.


  • What is one advancement in your field you’d like to see in your career?


I’d love to see my field get a better understanding of how juxtacrine and paracrine interactions between the alveolar epithelium and immune cells bear on alveolar injury and repair mechanisms.  Although major progress has been made toward understanding global immune responses in the lung, it would be helpful to gain a better appreciation of the more granular, spatial and temporal dynamics of the cell-cell communication that underlies alveolar responses.


  • Which statement did you make up?


#3.  This is definitely not true.  I’m not very good, but I do love to play.  We should get a group together at the next ATS.